Food Additive Cooling Agent Coolada WS-12 Powder CAS:68489-09-8
|Place of Origin:||Shan'xi|
|Brand Name:||Xi'an Taima|
|Model Number:||Cooling Agent WS-12|
Payment & Shipping Terms:
|Minimum Order Quantity:||500g|
|Packaging Details:||1kg for Aluminum foil bag and 25kg Fiber drum|
|Delivery Time:||1-5 work days|
|Payment Terms:||T/T,Western Union,Paypal|
|Supply Ability:||100,000kg per month|
|CAS Number:||68489-09-8||Chemical Name:||Cyclohexanecarboxamide, N-(4-methoxyphenyl)-5-methyl-2-(1-methylethyl)-, (1R, 2S, 5R)-|
|Coler:||White Powder||Empirical Formular:||C18H27NO2|
|Odor:||Mild Cooling, Slight Menthol Odor, Almost Odorless.||Purity:||99.0% Min|
|Melting Point:||177℃ – 181℃||Package:||Aluminum Foil Bag|
|Storage:||Store In Dry, Tightly Closed Containers. Keep Out Of Direct Sunlight.|
food grade cooler
Cooling Agent WS-12 -
What's Cooling Agent WS-12?
Taima Cooling Agent WS-12 powder is a potent TRPM8 agonist that acts as a cooling agent (EC50 = 193 nM). It robustly activated TRPM8 in low micromolar concentrations (EC50 12+/-5 microM) thereby displaying a higher potency and efficacy compared to menthol (EC50 196+/-22 microM). The selectivity profile of WS-12, its several-fold higher potency and around two-fold increase in efficacy compared to menthol warrants its potential utility for therapy in chronic neuropathic pain states and as a diagnostic probe in prostate cancer.
It is a menthol derivative. But unlike menthol, it is virtually nonvolatile, odorless and tasteless. It offers one of the strongest initial cooling impacts and a significantly longer lasting effect comparing with such conventional coolants such as WS-3, WS-5, and WS-23. It has potential for use in mint flavors in oral care applications as well as confectionary and chewing gum depending on dosage levels. In addition it can be used at low levels to impart freshness into berry, citrus and other fruit flavors in a variety of applications. WS-12 has been found to cool primarily at the front of the tongue.
Cooling Agent Powder Inner pacakge (1kg)
5kg Package 25kg Package
1. Daily use products: toothpaste, oral products, Air Freshener, skin cream, shaving cream, shampoo, sunscreen, shower cream.
2. Food products: confectionery products, chocolate, dairy produce, beer, distilled spirit, beverage, Chewing Gum.
3. Medicine: linctus, diminish inflammation ointment, dyspepsia, antipruritic, liniment, oral cavity acesodyne, heatstroke pill.
4. Others: cigarette, filter tip and other tobacco, it also can be used for driving insects.
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